CAS No.: 1049704-18-8
7-((4-Chlorobenzyl)amino)-1-tosyl-3,4-dihydropyrrolo[4,3,2-de]quinolin-8(1H)-one 2,2,2-trifluoroacetate Catalog No. CSN26552
Synonyms: MA242
MA242 is a Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy. MA242 decreased cell proliferation and induced apoptosis in pancreatic cancer cell lines regardless of p53 status. MA242 alone or in combination with gemcitabine inhibited pancreatic tumor growth and metastasis without any host toxicity. Our data indicate that targeting both MDM2 and NFAT1 represents a novel and effective strategy to treat pancreatic cancer.
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纯度 & 质量文件
批次:
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生物活性
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技术信息
| CAS号 | 1049704-18-8 | 储存条件 |
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| 分子式 | C26H21ClF3N3O5S | 运输 | 蓝冰 | |
| 分子量 | 579.98 | 别名 | MA242 |
